Joel are Magic put out a pre-release check on Star Trek collector boxes, and his answer is short. Wait. He has the boxes at 569 dollars on TCGplayer Market three weeks before release, against a 456 dollar sticker price. That is still a premium, after a fall from 694 dollars in late September. The title says dropped 125 dollars, and the math checks out.
He looks back at the last five Universes Beyond collector boxes. Four of them, Spider-Man, Avatar, Teenage Mutant Ninja Turtles, and Marvel Super Heroes, were back at sticker or under it within about five weeks of release. The Hobbit is the exception, still above sticker but down about 20 percent in two months. His call: wait for 456 dollars or mid-December, whichever comes first. An MSRP preorder from a local game store removes the wait, and for sealed holders he would skip it outright.
Wizards lists the Star Trek collector booster at 37.99 dollars, and a box holds twelve packs, which works out to about 456 dollars. So 569 dollars is still roughly 113 dollars over sticker. The set does not hit tables until November 13, with prerelease from November 6 to 12, and the full card gallery does not arrive until November 30. Early buyers are paying a premium while the full card pool is still unrevealed, including the Stardates bonus sheet and the LCARS shock lands Commander players will chase.
It depends what you are doing. If you want to open a box, do not pay the pre-release premium unless you have a reason to open it early. A sticker preorder, or a wait until December, gets you the same cardboard for less. If you are a seller holding pre-release stock, pricing near the falling market beats holding out for the premium. And if you are buying sealed to sit on, Joel's skip looks honest. A box already sliding before release is a hard hold.
Source: Joel are Magic, "Star Trek Collector Boxes Dropped $125 Before Release" https://www.youtube.com/watch?v=cuVFayP9l24